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Penicillium chrysogenum (formerly known as Penicillium notatum) is a species of fungus in the genus Penicillium.It is common in temperate and subtropical regions and can be found on salted food products, [1] but it is mostly found in indoor environments, especially in damp or water-damaged buildings. [2]
[10] [11] The Seventeenth International Botanical Congress held in Vienna, Austria, in 2005 adopted the name P. chrysogenum as the conserved name (nomen conservandum). [12] Whole genome sequence and phylogenetic analysis, particularly using β-tubulin sequences, in 2011 showed that P. notatum is P. rubens, and that P. chrysogenum is a different ...
Penicillium chrysogenum: fungus: meat sausage [5] Penicillium commune: fungus: cheese (surface-ripened) [2] [4] Penicillium nalgiovense: fungus: cheese [2 ...
Penicillin, a drug produced by P. chrysogenum (formerly P. notatum), was accidentally discovered by Alexander Fleming in 1929, and found to inhibit the growth of Gram-positive bacteria (see beta-lactams). Its potential as an antibiotic was realized in the late 1930s, and Howard Florey and Ernst Chain purified and concentrated the compound.
Most penicillins in clinical use are synthesised by P. chrysogenum using deep tank fermentation [2] and then purified. [ 3 ] [ 4 ] A number of natural penicillins have been discovered, but only two purified compounds are in clinical use: penicillin G ( intramuscular or intravenous use ) and penicillin V (given by mouth).
[33] [34] To resolve the confusion, the Seventeenth International Botanical Congress held in Vienna, Austria, in 2005 formally adopted P. chrysogenum as the name. [35] Whole-genome sequence and phylogenetic analysis in 2011 revealed that Fleming's mould belongs to P. rubens, a species described by Belgian microbiologist Philibert Biourge in ...
P. tardochrysogenum. Binomial name; Penicillium tardochrysogenum. Frisvad, Houbraken & Samson 2012 [1] Type strain; CBS 132200, DTO 149-B9, DTO 149B9, IBT 30075 [2]
But Thom adopted and popularised the use of P. chrysogenum. [18] In addition to P. notatum, newly discovered species such as P. meleagrinum and P. cyaneofulvum were recognised as members of P. chrysogenum in 1977. [19] To resolve the confusion, the Seventeenth International Botanical Congress held in Vienna, Austria, in 2005 formally adopted ...