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The desired tissue for insulin delivery is the subcutaneous (SC) fat because insulin absorption (pharmacokinetics [PK]) and action (pharmacodynamics [PD]) in the SC space are much more consistent than when it is delivered as an intramuscular (IM) injection.
Insulin and some hormones are commonly administered as subcutaneous injections. Other drugs that need to be given very quickly can also be administered via subcutaneous injection....
A subcutaneous injection uses a short needle to inject a mediation into the fatty tissue layer between your skin and muscle — or right under your skin. Typically, medication delivered this way is absorbed by your body slowly, around 24 hours after the injection.
Insulin is injected subcutaneously, which means into the fat layer under the skin. In this type of injection, a short needle is used to inject insulin into the fatty layer between the skin and...
Variability in the effect of subcutaneously administered insulin represents a major challenge in insulin therapy where precise dosing is required in order to achieve targeted glucose levels.
Insulin is a peptide hormone secreted in the body by beta cells of islets of Langerhans of the pancreas and regulates blood glucose levels. Medical treatment with insulin is indicated when there is inadequate production or increased insulin demands in the body. [1] The FDA-approved indications for treatment with insulin are as follows.
Common injection sites. A person needs to inject insulin into the layer of fat directly under the skin, known as subcutaneous tissue. An individual does this with a small needle or a device...