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Section of human adrenal gland under the microscope, showing its different layers. From the surface to the center: zona glomerulosa, zona fasciculata, zona reticularis, medulla. In the medulla, the central adrenomedullary vein is visible. The adrenal cortex is the outer region and also the largest part of an adrenal gland.
Diagram showing the position of the adrenal glands. Date: 30 July 2014 (released by CRUK) Source: Original email from CRUK: Author: Cancer Research UK: Permission (Reusing this file) This image has been released as part of an open knowledge project by Cancer Research UK. If re-used, attribute to Cancer Research UK / Wikimedia Commons
The adrenal cortex is the outer region and also the largest part of the adrenal gland. It is divided into three separate zones: zona glomerulosa, zona fasciculata and zona reticularis. Each zone is responsible for producing specific hormones. It is also a secondary site of androgen synthesis. [2]
The renal fascia is a dense, elastic connective tissue envelope enclosing the kidney and adrenal gland, together with the layer of perirenal fat surrounding these two. [1]The renal fascia separates the adipose capsule of kidney from the overlying pararenal fat.
The zona glomerulosa (sometimes, glomerular zone) of the adrenal gland is the most superficial layer of the adrenal cortex, lying directly beneath the renal capsule. Its cells are ovoid and arranged in clusters or arches (glomus is Latin for "ball"). [citation needed] H & E staining of the adrenal cortex.
It is located at the center of the gland, being surrounded by the adrenal cortex. [1] It is the innermost part of the adrenal gland, consisting of chromaffin cells that secrete catecholamines , including epinephrine (adrenaline), norepinephrine (noradrenaline), and a small amount of dopamine , in response to stimulation by sympathetic ...
On top of each kidney is an adrenal gland. The upper parts of the kidneys are partially protected by the 11th and 12th ribs. Each kidney, with its adrenal gland is surrounded by two layers of fat: the perirenal fat present between renal fascia and renal capsule and pararenal fat superior to the renal fascia.
At this location, in the wall of the last portion of distal straight tubule, there is a modified region of tubular epithelium called the macula densa.(Fig. 5 in Kumaran and Hanukoglu 2020) [5] Cells in the macula densa respond to changes in the sodium chloride levels in the distal tubule of the nephron via the tubuloglomerular feedback (TGF) loop.