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  2. Nephron - Wikipedia

    en.wikipedia.org/wiki/Nephron

    The nephron is the functional unit of the kidney. [3] This means that each separate nephron is where the main work of the kidney is performed. A nephron is made of two parts: a renal corpuscle, which is the initial filtering component, and; a renal tubule that processes and carries away the filtered fluid. [4]: 1024

  3. Glomerular filtration rate - Wikipedia

    en.wikipedia.org/wiki/Glomerular_filtration_rate

    Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [4] Central to the physiologic maintenance of GFR is the differential basal tone of the afferent (input) and efferent (output) arterioles (see diagram).

  4. Assessment of kidney function - Wikipedia

    en.wikipedia.org/wiki/Assessment_of_kidney_function

    The glomerular filtration rate (GFR) describes the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [3] Creatinine clearance (C Cr ) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR.

  5. Glomerulus (kidney) - Wikipedia

    en.wikipedia.org/wiki/Glomerulus_(kidney)

    The glomerulus and its surrounding Bowman's capsule constitute a renal corpuscle, the basic filtration unit of the kidney. [2] The rate at which blood is filtered through all of the glomeruli, and thus the measure of the overall kidney function, is the glomerular filtration rate.

  6. Renal physiology - Wikipedia

    en.wikipedia.org/wiki/Renal_physiology

    Volume of blood plasma delivered to the kidney per unit time. PAH clearance is a renal analysis method used to provide an estimate. Approximately 625 ml/min. renal blood flow = (HCT is hematocrit) Volume of blood delivered to the kidney per unit time. In humans, the kidneys together receive roughly 20% of cardiac output, amounting to 1 L/min in ...

  7. Urinary system - Wikipedia

    en.wikipedia.org/wiki/Urinary_system

    The first step in urine formation is the filtration of blood in the kidneys. In a healthy human, the kidney receives between 12 and 30% of cardiac output, but it averages about 20% or about 1.25 L/min. The basic structural and functional unit of the kidney is the nephron.

  8. Renal corpuscle - Wikipedia

    en.wikipedia.org/wiki/Renal_corpuscle

    These pedicels interdigitate with pedicels of adjacent podocytes forming filtration slits. There are two poles in the renal corpuscle, a vascular pole and a tubular pole. [4] The vascular pole is a location of the glomerulus. At the vascular pole, the afferent arterioles and efferent arterioles enter and leave the glomerulus in the Bowman's ...

  9. Filtration coefficient - Wikipedia

    en.wikipedia.org/wiki/Filtration_coefficient

    Typical units of Kf are mL/min/mmHg. The rate of filtration across the membrane is, by definition, the product of Kf and the net filtration pressure across the membrane. [1] [2] [3] Kf is frequently applied to the glomerular capillaries, which filter water into Bowman's capsule to form urine. Typically, in an adult human, the net filtration ...