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Chromium(III) picolinate (also trivalent chromium) is a chemical compound with the formula Cr(C 5 H 4 N(CO 2)) 3, commonly abbreviated as CrPic 3. It is a bright-red coordination compound derived from chromium (III) and picolinic acid .
Chromium picolinate is the form of chromium found in most over-the-counter supplements, and it's been used to help manage blood sugar levels in people with pre-diabetes, insulin resistance, or ...
Dietary supplements containing chromium are widely available in the United States, with claims for benefits for fasting plasma glucose, hemoglobin A1C and weight loss. Reviews report the changes as modest, and without scientific consensus that the changes have a clinically relevant impact.
The natural form of chromium from yeast (GTF chromium) is has better-established health effects, and is cheaper. GTF chromium is not patented, because it cannot be - it's a natural substance. Chromium Picolinate was an attempt to profit by patenting an analogue to the beneficial GTF chromium, and it was heavily promoted based on very thin ...
Chromium(III) nicotinate is an ionic substance used for chromium supplementation in some nutritional products, where it is also referred to as chromium polynicotinate. It appears in products that are referred to as a medical food used for nutritional support for conditions associated with diabetes mellitus type 2 .
A large number of chromium(III) compounds are known, such as chromium(III) nitrate, chromium(III) acetate, and chromium(III) oxide. [33] Chromium(III) can be obtained by dissolving elemental chromium in acids like hydrochloric acid or sulfuric acid , but it can also be formed through the reduction of chromium(VI) by cytochrome c7 . [ 34 ]
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Sun Y, Ramirez J, Woski SA, Vincent JB: The binding of trivalent chromium to low-molecular-weight chromium-binding substance (LMWCr) and the transfer of chromium from transferrin and chromium picolinate to LMWCr. J Biol Inorg Chem 5: 129–136, 2000 5. Schwarz K, Mertz W: A glucose tolerance factor and its differentiation from factor 3.