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The Tet-On Advanced transactivator (also known as rtTA2 S-M2) is an alternative version of Tet-On that shows reduced basal expression, and functions at a 10-fold lower Dox concentration than Tet-Off. In addition, its expression is considered to be more stable in eukaryotic cells due to being human codon optimized and utilizing three minimal ...
The transactivator gene expresses a transcription factor that binds to specific promoter region of DNA. By binding to the promoter region of a gene, the transcription factor causes that gene to be expressed. The expression of one transactivator gene can activate multiple genes, as long as they have the same, specific promoter region attached.
SCSI—Small Computer System Interface; SCTP—Stream Control Transmission Protocol; SD—Secure Digital; SDDL—Security Descriptor Definition Language; SDH—Synchronous Digital Hierarchy; SDI—Single-Document Interface; SEC—Single Edge Contact; SDIO—Secure Digital Input Output; SDK—Software Development Kit; SDL—Simple DirectMedia Layer
Rev is a transactivating protein that is essential to the regulation of HIV-1 (and other lentiviral) protein expression.A nuclear localization signal is encoded in the rev gene, which allows the Rev protein to be localized to the nucleus, where it is involved in the export of unspliced and incompletely spliced mRNAs.
Pictures and films created using computers. Usually, the term refers to computer-generated image data created with the help of specialized graphical hardware and software. It is a vast and recently developed area of computer science. computer network. Also data network. A digital telecommunications network which allows nodes to share resources.
In one sense, the answers to uncertainties. input/output (I/O) That part of a computer system devoted to exporting and importing data, for example, in human-readable form. inrush current The transient current that flows when first connecting a device to a power source. Institute of Electrical and Electronics Engineers (IEEE)
The TET enzymes are a family of ten-eleven translocation (TET) methylcytosine dioxygenases. They are instrumental in DNA demethylation . 5-Methylcytosine (see first Figure) is a methylated form of the DNA base cytosine (C) that often regulates gene transcription and has several other functions in the genome.
Like other lentiviruses, HIV-1 encodes a trans-activating regulatory protein (Tat), which is essential for efficient transcription of the viral genome. [7] [8] Tat acts by binding to an RNA stem-loop structure, the trans-activation response element (TAR), found at the 5′ ends of nascent HIV-1 transcripts.