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Continuous flow centrifugation (CFC) historically required two venipunctures as "continuous" means the blood is collected, spun, and returned simultaneously. Newer systems can use a single venipuncture by pooling blood in a vessel and cycling through drawing and returning blood though the needle while the centrifuge continuously processes blood remaining in the vessel. [5]
This procedure has been deemed controversial at times, especially when used by athletes.In 2005, the World Anti-Doping Agency ruled that blood-spinning could be used to introduce banned substances, [2] and in 2010 the agency went as far as banning the use of intramuscular injections of PRP in competitive athletes amid some concerns that it boosted performance-enhancing growth factors. [3]
Erythrocytapheresis can also be used for blood donations. The procedure is commonly done using automated red blood cell collection which involves the removal of two units of red blood cells. This includes either two standard units of red blood cells or one unit plus of red blood cells and another of either plasma or platelets.
a clear solution of blood plasma in the upper phase (which can be separated into its own fractions, see Blood plasma fractionation), the buffy coat, which is a thin layer of leukocytes (white blood cells) mixed with platelets in the middle, and; erythrocytes (red blood cells) at the bottom of the centrifuge tube.
It is thus an extracorporeal therapy, a medical procedure performed outside the body. [1] Three general types of plasmapheresis can be distinguished: Autologous, removing blood plasma, treating it in some way, and returning it to the same person, as a therapy. Exchange, a patient's blood plasma is removed, while blood products are given in ...
Blood plasma is a light amber-colored liquid component of blood in which blood cells are absent, but which contains proteins and other constituents of whole blood in suspension. It makes up about 55% of the body's total blood volume. [ 1 ]