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An infectious disease agent can be transmitted in two ways: as horizontal disease agent transmission from one individual to another in the same generation (peers in the same age group) [3] by either direct contact (licking, touching, biting), or indirect contact through air – cough or sneeze (vectors or fomites that allow the transmission of the agent causing the disease without physical ...
The classical process of infection of a cell by a virion can be called "cell-free spread" to distinguish it from a more recently recognized process called "cell-to-cell spread". [90] In cell-free spread (see figure), virus particles bud from an infected T cell, enter the blood or extracellular fluid and then infect another T cell following a ...
Sewage contaminated water contains many viruses, over one hundred species are reported and can lead to diseases that affect human beings. For example, hepatitis, gastroenteritis, meningitis, fever, rash, and conjunctivitis can all be spread through contaminated water. More viruses are being discovered in water because of new detection and ...
After the virus enters the body there is a period of rapid viral replication, leading to an abundance of virus in the peripheral blood. During primary infection, the level of HIV may reach several million virus particles per milliliter of blood. [2] This response is accompanied by a marked drop in the numbers of circulating CD4 + T cells.
HIV can also disseminate by direct transmission from one cell to another by a process of cell-to-cell spread. [96] [97] The hybrid spreading mechanisms of HIV contribute to the virus' ongoing replication against antiretroviral therapies. [95] [98] Two types of HIV have been characterized: HIV-1 and HIV-2. HIV-1 is the virus that was originally ...
Relevant microbes may be viruses, bacteria, or fungi, and they may be spread through breathing, talking, coughing, sneezing, spraying of liquids, toilet flushing or any activities which generate aerosol particles or droplets or generate fomites, such as raising of dust. [13] [14]
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