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Statins are linked to better health outcomes in older adults over the age of 70 with or without previous cardiovascular disease, a new study finds. Older adults over age 70 should consider taking ...
Cholesterol synthesis appears to occur mostly at night, [139] so statins with short half-lives are usually taken at night to maximize their effect. Studies have shown greater LDL and total cholesterol reductions in the short-acting simvastatin taken at night rather than the morning, [ 140 ] [ 141 ] but have shown no difference in the long ...
To better understand statin use in older adults, the researchers evaluated the health records of adults over 60 who had not previously been diagnosed with heart disease but met indications to ...
A recent study by the National Center for Health Statistics revealed that a higher percentage of women 20 and older have high total cholesterol than men in the same age group, and the rates ...
The effects of rosuvastatin on low-density lipoprotein (LDL) cholesterol are dose-related. Higher doses were more efficacious in improving the lipid profile of patients with hypercholesterolemia than milligram-equivalent doses of atorvastatin and milligram-equivalent or higher doses of simvastatin and pravastatin.
Type 2 statins Statins that are fully synthetic and have larger groups linked to the HMG-like moiety are often referred to as type 2 statins. One of the main differences between the type 1 and type 2 statins is the replacement of the butyryl group of type 1 statins by the fluorophenyl group of type 2 statins.
These guidelines recommend statin therapy for adults between forty and seventy-five who have diabetes, high cholesterol levels, or an estimated 10-year atherosclerotic cardiovascular disease risk ...
Statin-induced rhabdomyolysis is rare, occurring in less than 0.1% of people who take statins. [64] [65] [66] Statin induced rhabdomyolysis, as with other statin associated muscle symptoms, occurs most commonly in the first year of treatment but can occur at any time during treatment. [64]