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  2. Ropeginterferon alfa-2b - Wikipedia

    en.wikipedia.org/wiki/Ropeginterferon_alfa-2b

    Ropeginterferon alfa-2b can cause liver enzyme elevations, low levels of white blood cells, low levels of platelets, joint pain, fatigue, itching, upper airway infection, muscle pain and flu-like illness. [3] Side effects may also include urinary tract infection, depression and transient ischemic attacks (stroke-like attacks). [3]

  3. Splenomegaly - Wikipedia

    en.wikipedia.org/wiki/Splenomegaly

    Splenomegaly is an enlargement of the spleen. [1] The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen.Splenomegaly is one of the four cardinal signs of hypersplenism which include: some reduction in number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any combination; a compensatory proliferative response in the bone marrow; and the ...

  4. Wandering spleen - Wikipedia

    en.wikipedia.org/wiki/Wandering_spleen

    The usual treatment is splenopexy, fixation of the spleen, but if there is no blood flow after unwinding the spleen through detorsion then splenectomy must be performed. [6] Although there have been few reported cases of treatment through laparoscopic surgery due to the rarity of the disease, it has been proven to be an effective surgical ...

  5. Organomegaly - Wikipedia

    en.wikipedia.org/wiki/Organomegaly

    Splenomegaly: Medical imaging: Largest dimension of over 11 cm, [27] [28] or craniocaudal height of 13 [29] cm. Moderate splenomegaly: the largest dimension is between 11–20 cm [27] Severe splenomegaly: the largest dimension is greater than 20 cm [27] Autopsy: Weight over upper limit of standard reference range, of 230 g (8.1 oz) [12] [13 ...

  6. Spleen pain - Wikipedia

    en.wikipedia.org/wiki/Spleen_pain

    Splenomegaly can result in hematologic disturbances and abdominal pain and can increase the risk for splenic rupture, which also causes spleen pain, from blunt trauma, resulting in life-threatening internal bleeding. [2] Many conditions can cause splenomegaly, such as various infections, liver disease, and cancer. [2]

  7. Splenic infarction - Wikipedia

    en.wikipedia.org/wiki/Splenic_infarction

    Other causes of splenomegaly (for example, Gaucher disease or hemoglobinopathies) can also predispose to infarction. Splenic infarction can also result from a sickle cell crisis in patients with sickle cell anemia. Both splenomegaly and a tendency towards clot formation feature in this condition.

  8. Tropical splenomegaly syndrome - Wikipedia

    en.wikipedia.org/wiki/Tropical_splenomegaly_syndrome

    Tropical splenomegaly syndrome, also known as hyperreactive malarial splenomegaly, occurs due immunological overstimulation to repeated attacks of malarial infection over a long period of time. [1] Condition is usually seen in malaria-endemic areas like Africa and Indian subcontinent. [ 2 ]

  9. Hepatosplenomegaly - Wikipedia

    en.wikipedia.org/wiki/Hepatosplenomegaly

    Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly). Hepatosplenomegaly can occur as the result of acute viral hepatitis, infectious mononucleosis, and histoplasmosis or it can be the sign of a serious and life-threatening lysosomal storage disease.