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Protease-activated receptors (PAR) are a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular domain. They are highly expressed in platelets , and also on endothelial cells , fibroblasts, immune cells, myocytes , neurons , and tissues that line the gastrointestinal tract.
2149 14062 Ensembl ENSG00000181104 ENSMUSG00000048376 UniProt P25116 P30558 RefSeq (mRNA) NM_001992 NM_001311313 NM_010169 RefSeq (protein) NP_001298242 NP_001983 NP_034299 Location (UCSC) Chr 5: 76.72 – 76.74 Mb Chr 13: 95.74 – 95.75 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Proteinase-activated receptor 1 (PAR1) also known as protease-activated receptor 1, coagulation ...
In algebra, the partial fraction decomposition or partial fraction expansion of a rational fraction (that is, a fraction such that the numerator and the denominator are both polynomials) is an operation that consists of expressing the fraction as a sum of a polynomial (possibly zero) and one or several fractions with a simpler denominator.
The RXR also forms a heterodimer with a number of other receptors (e.g., vitamin D and thyroid hormone). The function of PPARs is modified by the precise shape of their ligand-binding domain (see below) induced by ligand binding and by a number of coactivator and corepressor proteins, the presence of which can stimulate or inhibit receptor ...
Detail of a human metaphase spread. A region in the pseudoautosomal region of the short arms of the X chromosome (left) and the Y chromosome (top right) was detected by fluorescent in situ hybridization (green).
Possessive forms are not often needed, but can be formed using apostrophe + s. Often the writer can also recast the sentence to avoid it. Example: BP's effect on risk of MI is multifaceted. The effect of BP on MI risk is multifaceted.
The wedge product of complex differential forms is defined in the same way as with real forms. Let p and q be a pair of non-negative integers ≤ n. The space Ω p,q of (p, q)-forms is defined by taking linear combinations of the wedge products of p elements from Ω 1,0 and q elements from Ω 0,1. Symbolically,
If such nicks persist unrepaired until DNA is replicated (which must precede cell division), then the replication itself can cause double strand breaks to form. [18] The main function of PARP (located in the cell nucleus) is to detect and initiate an immediate cellular response to metabolic, chemical, or radiation-induced single-strand DNA ...