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Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes, or symptomatic heart failure.
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Antidepressant discontinuation syndrome, also called antidepressant withdrawal syndrome, is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication following its continuous use of at least a month. [5]
The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...
Physiological causes could include a pheochromocytoma, heart attack, blood transfusion, anaphylaxis, [1] or use of some psychoactive substances. [2] The feeling can also be a transient side effect of adenosine administration, likely due to its activation of adenosine receptors. Due to adenosine's extremely short half-life, this effect is ...
The people taking the GLP-1 drugs also had increased GI-related issues, low blood pressure, and arthritis, as well as certain kidney conditions and pancreatitis—most of which are already known ...
The 1990s was an iconic decade. We had bops being released left and right by Oasis, the Spice Girls, Snoop Dogg and more. You could catch Pulp Fiction, Clueless, Forrest Gump and Titanic in movie ...
In some cases, a drug can cause the immune system to mistakenly think the body's own red blood cells are dangerous, foreign substances. Antibodies then develop against the red blood cells. The antibodies attach to red blood cells and cause them to break down too early. It is known that more than 150 drugs can cause this type of hemolytic anemia ...