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Sulfanilamide (also spelled sulphanilamide) is a sulfonamide antibacterial drug. Chemically, it is an organic compound consisting of an aniline derivatized with a sulfonamide group. [1] Powdered sulfanilamide was used by the Allies in World War II to reduce infection rates and contributed to a dramatic reduction in mortality rates compared to ...
The progestogen challenge test, or progesterone withdrawal test, is a test used in the field of obstetrics and gynecology to evaluate a patient who is experiencing amenorrhea. Due to readily available assays to measure serum estradiol levels, this test is now rarely used.
Sulfasalazine, sold under the brand name Azulfidine among others, is a medication used to treat rheumatoid arthritis, ulcerative colitis, and Crohn's disease. [5] It is considered by some to be a first-line treatment in rheumatoid arthritis. [6] It is taken by mouth or can be administered rectally. [5]
Sulfonamide functional group Hydrochlorothiazide is a sulfonamide and a thiazide. Furosemide is a sulfonamide, but not a thiazide. Sulfamethoxazole is an antibacterial sulfonamide. Sulfonamide is a functional group (a part of a molecule) that is the basis of several groups of drugs, which are called sulphonamides, sulfa drugs or sulpha drugs.
It is approved in the United States as a treatment and preventive measure against malaria. [6] The combination is considered to be more effective in treating malaria caused by Plasmodium falciparum than that caused by P. vivax, for which chloroquine is considered more effective, though in the absence of a species-specific diagnosis, the sulfadoxine-pyrimethamine combination may be indicated. [7]
The structure of the sulfonamide group. In organic chemistry, the sulfonamide functional group (also spelled sulphonamide) is an organosulfur group with the structure R−S(=O) 2 −NR 2. It consists of a sulfonyl group (O=S=O) connected to an amine group (−NH 2). Relatively speaking this group is unreactive.
Its use during pregnancy is contraindicated, although it has been placed in Australian pregnancy category C. [13] Its use during the first trimester (during organogenesis) and 12 weeks prior to pregnancy has been associated with an increased risk of congenital malformations, especially malformations associated with maternal folic acid ...
Dapsone is commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. [4] It is also used to both treat and prevent pneumocystis pneumonia (PCP). [4] [10] It is also used for toxoplasmosis in people unable to tolerate trimethoprim with sulfamethoxazole. [10]