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For patients with more than 1,000 PVCs per day, the risk of developing left ventricular systolic dysfunction after 5 years follow-up is low. Frequent PVCs may increase the risk of developing cardiomyopathy, which can greatly impair heart function. A PVC burden greater than 10% is the minimal threshold for development of PVC-induced cardiomyopathy.
The second Cardiac Arrhythmia Suppression Trial (CAST II) modified the enrollment criteria to include patients at higher risk for serious arrhythmia. [4] This included 1) patients enrolled within 4 to 90 days of a previous MI, 2) a left ventricular ejection fraction lower than 40%, 3) prior to enrollment, suppression of PVCs had occurred with the drugs (vs. placebo) using a double-blinded ...
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A premature heart beat or extrasystole [1] is a heart rhythm disorder corresponding to a premature contraction of one of the chambers of the heart. Premature heart beats come in two different types: premature atrial contractions and premature ventricular contractions.
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Ectopic beat is a disturbance of the cardiac rhythm frequently related to the electrical conduction system of the heart, in which beats arise from fibers or group of fibers outside the region in the heart muscle ordinarily responsible for impulse formation (i.e., the sinoatrial node).
When the atrial rhythm is irregular (as in atrial fibrillation or sinus arrhythmia) the presence of bigeminy depends on the length of the P–P interval and happens more frequently with a longer interval. As with post PVC pauses, a longer P–P interval leads to a higher chance of re-entrant circuits and thus PVCs.
Palpitations can be described in many ways. [1] The most common descriptions include a flip-flopping in the chest, a rapid fluttering in the chest, or pounding in the neck. [ 1 ] The description of the symptoms may provide a clue regarding the etiology of the palpitations, and the pathophysiology of each of these descriptions is thought to be ...