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Patients with interstitial cystitis may find relief by modifying their diet to remove foods and beverages that trigger symptoms: caffeinated beverages, particularly coffee (regular and decaf), tea, green tea, soda, artificial sugars and fruit juices. Cranberry juice may also trigger intense pain and discomfort.
In addition to hydrodistension related glomerulations, a study by Rosamilia et al. has shown that biopsied bladders from women with interstitial cystitis have decreased vessel density in the subepithelium. With this, data collected by Irwin et al. also showed that blood perfusion in interstitial cystitis bladders is reduced.
The term "interstitial cystitis" was coined by Dr. Alexander Skene in 1887 to describe the disease. [13] In 2002, the United States amended the Social Security Act to include interstitial cystitis as a disability. The first guideline for diagnosis and treatment of interstitial cystitis is released by a Japanese research team in 2009. [71]
In interstitial cystitis, pentosan polysulfate is believed to work by providing a protective coating to the damaged bladder wall. Pentosan polysulfate is similar in structure to the natural glycosaminoglycan coating of the inner lining of the bladder , and may replace or repair the lining, reducing its permeability .
Eosinophilic cystitis is a rare type of interstitial cystitis first reported in 1960 by Edwin Brown. [1] Eosinophilic cystitis has been linked to a number of etiological factors, including allergies , bladder tumors , trauma to the bladder, parasitic infections , and chemotherapy drugs , though the exact cause of the condition is still unknown.
A urinary tract infection (UTI) is an infection that affects a part of the urinary tract. [1] Lower urinary tract infections may involve the bladder (cystitis) or urethra while upper urinary tract infections affect the kidney (pyelonephritis). [10]