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Zanubrutinib, sold under the brand name Brukinsa, is an anticancer medication used for the treatment of mantle cell lymphoma (MCL), Waldenström's macroglobulinemia (WM), marginal zone lymphoma (MZL), and chronic lymphocytic leukemia (CLL).
In 2023, Brukinsa, the Bruton's tyrosine kinase inhibitor crossed blockbuster threshold to hit 1.3 billion dollars in full-year sales with the majority of product sales originating in the United States and Europe. [26] [27] Brukinsa is the only BTK inhibitor to demonstrate PFS supriority in a head-to-head comparison of BTK inhibitors. [28]
Brukinsa is approved in the United States to treat four other types of blood cancers and generated global sales of $1.3 billion last year.
A large flock of vultures can reduce human corpse or carcass of large animal to skeleton within few hours. After skeletonization, if scavenging animals do not destroy or remove the bones, acids in many fertile soils take about 20 years to completely dissolve the skeleton of mid- to large-size mammals, such as humans, leaving no trace of the ...
A decomposing human body in the earth will eventually release approximately 32 g (1.1 oz) of nitrogen, 10 g (0.35 oz) of phosphorus, 4 g (0.14 oz) of potassium, and 1 g (0.035 oz) of magnesium for every kilogram of dry body mass, making changes in the chemistry of the soil around it that may persist for years.
The average human can hold their breath for about 2 minutes, though most of us would struggle to get 1 minute without practice. Don’t feel bad though. Don’t feel bad though.
The benefits of walking abound—improving heart health, sleep quality, and mood are just a few of the many pros of going for a stroll. Now, new research has found that walking could add over 10 ...
Brucellosis in humans is usually associated with consumption of unpasteurized milk and soft cheeses made from the milk of infected animals—often goats—infected with B. melitensis, and with occupational exposure of laboratory workers, veterinarians, and slaughterhouse workers.