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Barrett's esophagus is a condition in which there is an abnormal (metaplastic) change in the mucosal cells lining the lower portion of the esophagus, from stratified squamous epithelium to simple columnar epithelium with interspersed goblet cells that are normally present only in the small intestine and large intestine.
Histopathology of Barrett's esophagus, showing intestinalized epithelium with Goblet cells, as opposed to normal stratified squamous epithelium of the esophagus, and pseudostratified columnar epithelium of the fundus of the stomach. H&E stain.
Incomplete intestinal metaplasia (incomplete Barrett's esophagus), showing both foveolar cells and goblet cells, latter indicated by arrows, and usually having a slightly bluish color compared to the apical cytoplasm of foveolar cells on H&E stain. Barrett's esophagus is a metaplasia of the esophagus into intestinal epithelium, characterized by ...
Involves in epithelial cell maturation as well as goblet and Paneth cell differentiation. Required for the small intestinal identity during development. In IEC-6 cells, conditional expression induced enterocyte and goblet like cells: 21081128 [13] 19386267 [14] 8552090 [15] CTNNB1: Catenin, beta: Paneth cell differentiation. Essential for stem ...
Squamous cell carcinoma* is a malignant tumor in dogs that most commonly occurs in the oral cavity, including the tongue, tonsils, and gingiva. Squamous cell carcinoma accounts for 5 percent of skin tumors in dogs, and are the most common tumor of the toe. Dogs with unpigmented skin on the nose may develop this cancer from long-term sun exposure.
They can occur in dogs of all ages, but are more likely in dogs under three years of age. Epidermal invasion by cells of histiocytoma frequently occurs and intra-epidermal nests of histiocytes resemble Pautrier's aggregates, characteristically found in epidermotropic lymphoma (Mycosis Fungoides or MF).
Hone Health unveils the logic behind the latest longevity trend: social wellness clubs.
Basal cells are the stem cells or progenitors of the airway epithelium and can differentiate to replenish all of the epithelial cells including the ciliated cells, and secretory goblet cells. [2] [3] This repairs the protective functions of the epithelial barrier. [3] Basal cells are cuboidal with a large nucleus, few organelles, and scattered ...