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Low concentrations of HDL (below 40 mg/dL for men, below 50 mg/dL for women) increase the risk for atherosclerotic diseases. [16] Data from the landmark Framingham Heart Study showed that, for a given level of LDL, the risk of heart disease increases 10-fold as the HDL varies from high to low. On the converse, however, for a fixed level of HDL ...
Hypocholesterolemia is the presence of abnormally low (hypo-) levels of cholesterol in the blood (-emia). A defect in the body's production of cholesterol can lead to adverse consequences as well. A defect in the body's production of cholesterol can lead to adverse consequences as well.
In those with loss-of-function variants in both copies of ANGPTL3, low LDL-C, low HDL-C, and low triglycerides are seen ("familial combined hypolipidemia"). [3] Hooft disease is a rare condition evidenced by low blood lipid level, red rash and mental and physical retardation. [citation needed]
Other functions of HDL-C is promoting cardiovascular health such as antioxidation effects, protection against thrombosis, maintenance of endothelial function, and maintaining low blood viscosity. [1] Due to the positive functions of HDL cholesterol, a low level indicates dyslipidemia and is a risk factor for complications. [1]
Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL). Metabolic syndrome is associated with the risk of developing cardiovascular disease and type 2 diabetes. [1]
Nearly 90% of adults over age 20 in the United States are at risk of developing heart disease, an alarming new study suggests.. While the unexpectedly high number doesn't mean that the majority of ...
Tangier disease or hypoalphalipoproteinemia is an extremely rare inherited disorder characterized by a severe reduction in the amount of high density lipoprotein (HDL), often referred to as "good cholesterol", in the bloodstream. [2] Worldwide, approximately 100 cases have even been identified. [3] [4]
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