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Selection coefficient, usually denoted by the letter s, is a measure used in population genetics to quantify the relative fitness of a genotype compared to other genotypes. . Selection coefficients are central to the quantitative description of evolution, since fitness differences determine the change in genotype frequencies attributable to selecti
The theorem was first formulated in Fisher's 1930 book The Genetical Theory of Natural Selection. [4] Fisher likened it to the law of entropy in physics, stating that "It is not a little instructive that so similar a law should hold the supreme position among the biological sciences".
Advanced Placement (AP) Biology (also known as AP Bio) is an Advanced Placement biology course and exam offered by the College Board in the United States. For the 2012–2013 school year, the College Board unveiled a new curriculum with a greater focus on "scientific practices".
Biostatistics (also known as biometry) is a branch of statistics that applies statistical methods to a wide range of topics in biology. It encompasses the design of biological experiments , the collection and analysis of data from those experiments and the interpretation of the results.
Kleiber's plot comparing body size to metabolic rate for a variety of species. [1]Kleiber's law, named after Max Kleiber for his biology work in the early 1930s, states, after many observations that, for a vast number of animals, an animal's Basal Metabolic Rate scales to the 3 ⁄ 4 power of the animal's mass.
Molecular biology is the study of molecular underpinnings of the biological phenomena, focusing on molecular synthesis, modification, mechanisms and interactions. The central dogma of molecular biology , where genetic material is transcribed into RNA and then translated into protein , despite being oversimplified, still provides a good starting ...
Phosphatidylinositol 4,5-bisphosphate or PtdIns(4,5)P 2, also known simply as PIP 2 or PI(4,5)P 2, is a minor phospholipid component of cell membranes. PtdIns(4,5)P 2 is enriched at the plasma membrane where it is a substrate for a number of important signaling proteins. [1]
Most cellular deconvolution algorithms consider an input data in a form of a matrix , which represents some molecular information (e.g. gene expression data or DNA methylation data) measured over a group of samples and marks (e.g. genes or CpG sites).