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Viscoelasticity of bone can arise from multiple factors related to structures on multiple length scales. [1] Bone is a composite of the bio-polymer collagen and the bio-ceramic hydroxyapatite. Additionally the collagen is plied in various directions around the bone. Bone has two structural forms; cortical and cancellous. [2]
Therefore, their mechanical properties are very important. Mechanical properties of some biomaterials and bone are summarized in Table 1. [2] Among them, hydroxyapatite is most widely studied bioactive and biocompatible material. However, it has lower Young's modulus and fracture toughness with a brittle nature. Hence, it is required to produce ...
The material needed for each application is different, and dependent on the desired mechanical properties of the material. Tissue engineering of long bone defects for example, will require a rigid scaffold with a compressive strength similar to that of cortical bone (100-150 MPa), which is much higher compared to a scaffold for skin regeneration.
Diagram of a typical long bone showing both compact (cortical) and cancellous (spongy) bone. Osteons on cross-section of a bone. In osteology, the osteon or haversian system (/ h ə ˈ v ɜːr. ʒ ən /; named for Clopton Havers) is the fundamental functional unit of much compact bone.
Mechanobiology is an emerging field of science at the interface of biology, engineering, chemistry and physics. It focuses on how physical forces and changes in the mechanical properties of cells and tissues contribute to development, cell differentiation, physiology, and disease. Mechanical forces are experienced and may be interpreted to give ...
There are several ways to obtain the material properties of each constituent: by identifying the behaviour based on molecular dynamics simulation results; by identifying the behaviour through an experimental campaign on each constituent; by reverse engineering the properties through a reduced experimental campaign on the heterogeneous material ...
The cortical bone gives bone its smooth, white, and solid appearance, and accounts for 80% of the total bone mass of an adult human skeleton. [10] It facilitates bone's main functions—to support the whole body, to protect organs, to provide levers for movement, and to store and release chemical elements, mainly calcium.
Biomechanical engineers can be seen as mechanical engineers that work in a biomedical context. This is not only due to occasionally mechanical nature of medical devices, but also mechanical engineering tools (such as numerical software packages ) are commonly used in analysis of biological materials and biomaterials due to the high importance ...