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Viscoelasticity of bone can arise from multiple factors related to structures on multiple length scales. [1] Bone is a composite of the bio-polymer collagen and the bio-ceramic hydroxyapatite. Additionally the collagen is plied in various directions around the bone. Bone has two structural forms; cortical and cancellous. [2]
Therefore, their mechanical properties are very important. Mechanical properties of some biomaterials and bone are summarized in Table 1. [2] Among them, hydroxyapatite is most widely studied bioactive and biocompatible material. However, it has lower Young's modulus and fracture toughness with a brittle nature. Hence, it is required to produce ...
A more recent definition (by Schroeder et al.) defines osseointegration as "functional ankylosis (bone adherence)", where new bone is laid down directly on the implant surface and the implant exhibits mechanical stability (i.e., resistance to destabilization by mechanical agitation or shear forces).
Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones. [2] In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). [3] It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells.
The cortical bone gives bone its smooth, white, and solid appearance, and accounts for 80% of the total bone mass of an adult human skeleton. [10] It facilitates bone's main functions—to support the whole body, to protect organs, to provide levers for movement, and to store and release chemical elements, mainly calcium.
Mesenchymal stem cell / marrow stromal cell; Chondrocyte; Hypertrophic chondrocyte; Mesenchymal (mesoderm origin) stem cells are undifferentiated, meaning they can differentiate into a variety of generative cells commonly known as osteochondrogenic (or osteogenic, chondrogenic, osteoprogenitor, etc.) cells.
There are several ways to obtain the material properties of each constituent: by identifying the behaviour based on molecular dynamics simulation results; by identifying the behaviour through an experimental campaign on each constituent; by reverse engineering the properties through a reduced experimental campaign on the heterogeneous material ...
The mechanical properties of the resulting porous scaffolds have been studied in various works of literature. [ 21 ] The printed 13-93 bioactive glass scaffold in the study by Liu et al. was dried in ambient air, fired to 600 °C under the O 2 atmosphere to remove the processing additives, and sintered in air for 1 hour at 700 °C.