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Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety , obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [ 1 ]
In an email to the Statesman and in an article for the Journal of the American Academy of Psychiatry and the Law, Harding wrote that while ketamine is common and has proved successful in clinical ...
Evidence is growing for the use of atypical psychedelics such as ketamine for treating depression in terminally ill patients, with repeated IV administration having the most therapeutic effect. [66] These studies did not have any patients experience any serious adverse effects; however, ketamine-induced ulcerative cystitis is a concern for ...
Ketamine has been tested as a rapid-acting antidepressant [13] for treatment-resistant depression in bipolar disorder, and major depressive disorder. [14] Spravato, a nasal spray form of esketamine, was approved by the FDA in 2019 for use in treatment-resistant depression when combined with an oral antidepressant. [15] [16]
Five subjects dropped out of the ketamine study; of these, four were taking valproate and one was being treated with lithium. One patient showed signs of hypomania following ketamine administration and two experienced low mood. This study demonstrates a rapid-onset antidepressant effect of ketamine in a small group of patients with bipolar ...
After a study published in the Journal of Clinical Psychology suggested that people who got ketamine IVs at three private ketamine infusion clinics had “significant improvement” in symptoms of ...
The more active enantiomer, esketamine (S-ketamine), is also available for medical use under the brand name Ketanest S, [136] while the less active enantiomer, arketamine (R-ketamine), has never been marketed as an enantiopure drug for clinical use. While S-ketamine is more effective as an analgesic and anesthetic through NMDA receptor ...
Some dissociative drugs are used recreationally. Ketamine and nitrous oxide are club drugs. Phencyclidine (PCP or angel dust) is available as a street drug. Dextromethorphan-based cough syrups (often labeled DXM) are taken by some users in higher than medically recommended levels for their dissociative effects.
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