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Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...
The symptoms of Cushing's disease are similar to those seen in other causes of Cushing's syndrome. [5] Patients with Cushing's disease usually present with one or more signs and symptoms secondary to the presence of excess cortisol or ACTH. [6] Although uncommon, some patients with Cushing's disease have large pituitary tumors (macroadenomas).
The activity of the cortisol and insulin can possibly activate Cushing's syndrome. [81] Hypothyroidism is a hormonal cause of obesity, but it does not significantly affect obese people who have it more than obese people who do not have it. In a comparison of 108 obese patients with hypothyroidism to 131 obese patients without hypothyroidism ...
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Depending on the degree of obesity and the presence of comorbid disorders, obesity is associated with an estimated 2–20 year shorter life expectancy. [ 37 ] [ 36 ] High BMI is a marker of risk for, but not a direct cause of, diseases caused by diet and physical activity.
According to the Mayo Clinic, the following are common symptoms of Cushing syndrome for both men and women: Weight gain in the trunk of the body, accompanied by thin arms and legs Weight gain in ...
[35] [36] Cushing's syndrome can either be exogenous or endogenous, depending on whether it is caused by an external or internal source, respectively. [37] The intake of glucocorticoids, a type of corticosteroid, is a common cause for the development of exogenous Cushing's syndrome. Endogenous Cushing's syndrome can occur when the body produces ...
Cushing syndrome, which is brought on by getting steroid injections in high doses, is characterized by a round, red and full face, as well as weight gain, thin skin and other symptoms.