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The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
Schizophrenia is a major cause of disability. In 2016, it was classed as the 12th most disabling condition. [237] Approximately 75% of people with schizophrenia have ongoing disability with relapses. [238] Some people do recover completely and others function well in society. [239]
In alternative medicine, some practitioners believe that there is a vast number of physical causes for the diagnosis of schizophrenia. [196] While some of these explanations may stretch credulity, others (such as heavy metal poisoning and nutritional imbalances) have been supported at least somewhat by research. [47] [197] [198]
'This will turn out to be the most important break in the disease,' the Broad Institute's director Eric Lander said.
This additional post-menopausal peak of late-onset schizophrenia in women calls into question the etiology of the disease and raises a debate about "subtypes" of schizophrenia, with men and women being susceptible to different types (see causes of schizophrenia). This is further supported by the variability in presentation of the disease ...
Schizophreniform disorder is a type of mental illness that is characterized by psychosis and closely related to schizophrenia.Both schizophrenia and schizophreniform disorder, as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR), have the same symptoms and essential features except for two differences: the level of functional impairment and the duration of symptoms.
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