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Etanercept mimics the inhibitory effects of naturally occurring soluble TNF receptors, the difference being that etanercept, because it is a fusion protein rather than a simple TNF receptor, has a greatly extended half-life in the bloodstream, and therefore a more profound and long-lasting biologic effect than a naturally occurring soluble TNF ...
The most common side effects of tramadol in order of decreasing incidence are: [1] [2 ... Serious adverse effects are in bold. Very common (>10% frequency) ...
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
Medication Side Effects. Some medications (including certain antidepressants) are known for side effects like weight gain. But some antidepressants are associated with weight loss, such as:
A Janssen executive complained that a J&J-funded article about Risperdal contained a “nauseating amount of information” about side effects. The study’s findings would immediately be circulated to the sales teams in the field and be formally published in the highly respected Journal of Child Psychiatry under the title, “Prolactin Levels ...
With that in mind, Janssen decided to push ahead with its own studies of whether Risperdal affected prolactin levels in children, and what side effects, if any, elevated prolactin might cause. At the same time, the company focused on rounding up respected academics who could aid the cause by touting the results as they came in and make ...
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