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Histologic image showing a section of epidermis. Stratum spinosum labeled slightly below center. The stratum spinosum (or spinous layer/prickle cell layer) [1] is a layer of the epidermis found between the stratum granulosum and stratum basale. [2] This layer is composed of polyhedral keratinocytes. [3] [4] These are joined with desmosomes. [3]
Keratinization is part of the physical barrier formation (cornification), in which the keratinocytes produce more and more keratin and undergo terminal differentiation. The fully cornified keratinocytes that form the outermost layer are constantly shed off and replaced by new cells.
The outer root sheath corresponds with the stratum mucosum (stratum germinativum and stratum spinosum) [1] of the epidermis, and resembles it in the rounded form and soft character of its cells; at the bottom of the hair follicle these cells become continuous with those of the root of the hair.
Microscopy of keratin filaments inside cells. Keratin (/ ˈ k ɛr ə t ɪ n / [1] [2]) is one of a family of structural fibrous proteins also known as scleroproteins.It is the key structural material making up scales, hair, nails, feathers, horns, claws, hooves, and the outer layer of skin in vertebrates.
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Histologic image of the epidermis with its layers named in white text.. The Malpighian layer (stratum mucosum or stratum malpighii) of the epidermis is generally defined as both the stratum basale (basal layer) and the thicker stratum spinosum (spinous layer/prickle cell layer) immediately above it as a single unit, [1] [2] although it is occasionally defined as the stratum basale specifically ...
An image being shared widely across Facebook, Instagram, and X (formerly Twitter) compares certain measures of the U.S. economy on the final day of Donald Trump’s presidency to current numbers ...
Keratinization is the differentiation of keratinocytes in the stratum granulosum into nonvital surface cells or squames to form the stratum corneum. The cells terminally differentiate as they migrate to the surface from the stratum basale where the progenitor cells are located to the superficial surface.