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Compounded tirzepatide is a formulation of tirzepatide — a medication for type 2 diabetes and weight loss. Tirzepatide is the active ingredient in the FDA-approved versions of the drug, Mounjaro ...
A new study explores the reasons why tirzepatide, the once-weekly injection used to treat obesity and type 2 diabetes, is associated with greater weight loss in women than men.
For the efficacy estimand, tirzepatide led to a 15.7% (in a combined population of people with and without type 2 diabetes) body weight reduction compared to 2.2% for placebo.
Tirzepatide [12] is an antidiabetic medication used for the treatment of type 2 diabetes [9] [13] [14] [15] and for weight loss. [ 10 ] [ 16 ] Tirzepatide is administered via subcutaneous injections (under the skin).
In the early 2020s, GLP-1 receptor agonists such as semaglutide or tirzepatide became popular for weight loss because they are more effective than earlier drugs, causing a shortage for patients prescribed these medications for type 2 diabetes, their original indication.
Preliminary trial results found a greater weight loss compared to either medication alone. HbA1c was significantly improved compared to cagrilintide alone and non-significantly better than semaglutide alone. [1] [2] In a Phase II trial, weight loss averaged -15.6 percent after 32 weeks, making CagriSema comparable in efficacy to tirzepatide.
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