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  2. Transcription factory - Wikipedia

    en.wikipedia.org/wiki/Transcription_factory

    Transcription factories, in genetics describe the discrete sites where transcription occurs in the cell nucleus, and are an example of a biomolecular condensate. They were first discovered in 1993 and have been found to have structures analogous to replication factories, sites where replication also occurs in discrete sites.

  3. Artificial transcription factor - Wikipedia

    en.wikipedia.org/wiki/Artificial_transcription...

    Figure 1. Example of a natural transcription factor up-regulating gene expression. 1. The transcription factors (labeled activator proteins) bind to their specific DNA sequence (labeled enhancers). 2. The transcription factors recruit other proteins and transcription factors to form a protein complex which binds to the gene promoter. 3.

  4. General transcription factor - Wikipedia

    en.wikipedia.org/wiki/General_transcription_factor

    The transcription preinitiation complex is a large complex of proteins that is necessary for the transcription of protein-coding genes in eukaryotes and archaea. It attaches to the promoter of the DNA (e.i., TATA box) and helps position the RNA polymerase II to the gene transcription start sites, denatures the DNA, and then starts transcription.

  5. Transcriptional regulation - Wikipedia

    en.wikipedia.org/wiki/Transcriptional_regulation

    transcriptional regulation – controlling the rate of gene transcription for example by helping or hindering RNA polymerase binding to DNA; transcription – the process of making RNA from a DNA template by RNA polymerase; transcription factor – a substance, such as a protein, that contributes to the cause of a specific biochemical reaction ...

  6. Transcription (biology) - Wikipedia

    en.wikipedia.org/wiki/Transcription_(biology)

    An example of such an antibacterial is rifampicin, which inhibits bacterial transcription of DNA into mRNA by inhibiting DNA-dependent RNA polymerase by binding its beta-subunit, while 8-hydroxyquinoline is an antifungal transcription inhibitor. [55]

  7. Activator (genetics) - Wikipedia

    en.wikipedia.org/wiki/Activator_(genetics)

    A transcriptional activator is a protein (transcription factor) that increases transcription of a gene or set of genes. [1] Activators are considered to have positive control over gene expression, as they function to promote gene transcription and, in some cases, are required for the transcription of genes to occur.

  8. Transcriptome - Wikipedia

    en.wikipedia.org/wiki/Transcriptome

    The transcriptome encompasses all the ribonucleic acid (RNA) transcripts present in a given organism or experimental sample. [8] RNA is the main carrier of genetic information that is responsible for the process of converting DNA into an organism's phenotype.

  9. Cis-regulatory element - Wikipedia

    en.wikipedia.org/wiki/Cis-regulatory_element

    An example of a cis-acting regulatory sequence is the operator in the lac operon. This DNA sequence is bound by the lac repressor, which, in turn, prevents transcription of the adjacent genes on the same DNA molecule. The lac operator is, thus, considered to "act in cis" on the regulation of the nearby genes.