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Single oral dose of nitroimidazole is sufficient to kill the parasites. [34] For 95–97% of cases, infection is resolved after one dose of metronidazole. [26] [35] Studies suggest that 4–5% of trichomonas cases are resistant to metronidazole, which may account for some "repeat" cases.
Metronidazole and its metabolites are mainly excreted via the kidneys (77%) and to a lesser extent via the faeces (14%). [7] [8] The biological half-life of metronidazole in healthy adults is eight hours, in infants during the first two months of their lives about 23 hours, and in premature babies up to 100 hours. [61]
Trichomonas vaginalis from a vaginal swab. This is a heavy infection; there were probably thousands of trichomonads in the vagina. Alfred Francois Donné (1801–1878) was the first to describe a procedure to diagnose trichomoniasis through "the microscopic observation of motile protozoa in vaginal or cervical secretions" in 1836.
Metronidazole is an antibiotic with an off-label use in eradicating H. pylori for treating gastric ulceration. Resistance of metronidazole is above 15% worldwide. [ 32 ] It is likely to be resistant so is not the first line choice of treatment. [ 44 ]
An antitrichomonal agent is an antiprotozoal agent that acts on trichomonas parasites. [1] Examples include: [2] furazolidone; nifuratel; nimorazole; ornidazole ...
Trichomonas vaginitis is an infection acquired through sex that is associated with vaginal discharge. [28] It can be transmitted by way of the penis to the vagina, the vagina to the penis, or from vagina to vagina. [32] The discharge in Trichomonas is typically yellowish-green in color. [28] It sometimes is frothy and can have a foul smell. [33]
Trichomoniasis is a common STI that is caused by infection with a protozoan parasite called Trichomonas vaginalis. [70] Trichomoniasis affects both women and men, but symptoms are more common in women. [71] Most patients are treated with an antibiotic called metronidazole, which is very effective. [72]
This antibiotic is not recommended for children and 75 and up of age: Inactivates enolpyruvyl transferase, thereby blocking cell wall synthesis Fusidic acid: Fucidin: Metronidazole: Flagyl: Infections caused by anaerobic bacteria; also amoebiasis, trichomoniasis, giardiasis: Discolored urine, headache, metallic taste, nausea; alcohol is ...