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Single oral dose of nitroimidazole is sufficient to kill the parasites. [34] For 95–97% of cases, infection is resolved after one dose of metronidazole. [26] [35] Studies suggest that 4–5% of trichomonas cases are resistant to metronidazole, which may account for some "repeat" cases.
Metronidazole and its metabolites are mainly excreted via the kidneys (77%) and to a lesser extent via the faeces (14%). [7] [8] The biological half-life of metronidazole in healthy adults is eight hours, in infants during the first two months of their lives about 23 hours, and in premature babies up to 100 hours. [61]
Trichomonas vaginalis from a vaginal swab. This is a heavy infection; there were probably thousands of trichomonads in the vagina. Alfred Francois Donné (1801–1878) was the first to describe a procedure to diagnose trichomoniasis through "the microscopic observation of motile protozoa in vaginal or cervical secretions" in 1836.
Trichomoniasis is a common STI that is caused by infection with a protozoan parasite called Trichomonas vaginalis. [70] Trichomoniasis affects both women and men, but symptoms are more common in women. [71] Most patients are treated with an antibiotic called metronidazole, which is very effective. [72]
Trichomonas vaginitis is an infection acquired through sex that is associated with vaginal discharge. [28] It can be transmitted by way of the penis to the vagina, the vagina to the penis, or from vagina to vagina. [32] The discharge in Trichomonas is typically yellowish-green in color. [28] It sometimes is frothy and can have a foul smell. [33]
Metronidazole is an antibiotic with an off-label use in eradicating H. pylori for treating gastric ulceration. Resistance of metronidazole is above 15% worldwide. [ 32 ] It is likely to be resistant so is not the first line choice of treatment. [ 44 ]
This antibiotic is not recommended for children and 75 and up of age: Inactivates enolpyruvyl transferase, thereby blocking cell wall synthesis Fusidic acid: Fucidin: Metronidazole: Flagyl: Infections caused by anaerobic bacteria; also amoebiasis, trichomoniasis, giardiasis: Discolored urine, headache, metallic taste, nausea; alcohol is ...
Disruption of the normal flora can cause a vaginal yeast infection. Vaginal yeast infection can affect women of all ages and is very common. The yeast Candida albicans is the most common cause of vaginitis. Specific forms of vaginal inflammation include the following types: Infectious vaginitis accounts for 90% of all cases in reproductive age ...