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The virus has coevolved in the bat host reservoir over a long period of time. [17] Only recently have strains of SARS-related coronavirus been observed to have evolved into having been able to make the cross-species jump from bats to humans, as in the case of the strains SARS-CoV-1 and SARS-CoV-2 .
Tests: The rate at which California’s COVID-19 tests are turning up positive has now exceeded last summer’s peak. For the seven-day period that ended July 22, 13.8% of coronavirus tests came ...
As H5N1 bird flu spreads among California dairy herds and southward-migrating birds, health officials announced Friday that six more human cases of infection: five in California and one in Oregon ...
SARS-CoV-2 shares amino acid identity with a furin cleavage site of human ENaC α subunit. [30] [31] [b] Human ENaC is identical only to that of a few great apes and Pipistrellus kuhli. [32] SARS-CoV-2 is also distinct among human coronaviruses for having a single intact ORF8 gene rather than "a" and "b" subunits. [1]
The San Francisco Bay Area, which includes the major cities of San Jose, San Francisco, and Oakland, was an early center of the COVID-19 pandemic in California. [2] The first case of COVID-19 in the area was confirmed in Santa Clara County on January 31, 2020. [3]
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Available evidence suggests that the SARS-CoV-2 virus was originally harbored by bats, and spread to humans from infected wild animals, functioning as an intermediate host, at the Huanan Seafood Market in Wuhan, Hubei, China, in December 2019. [39] [40] Several candidate animal species have been identified as potential intermediate hosts. [47]
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