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The interpretation of urinalysis takes into account the results of physical, chemical and microscopic examination and the person's overall condition. Urine test results should always be interpreted using the reference range provided by the laboratory that performed the test, or using information provided by the test strip/device manufacturer. [136]
Automatic analysis of urine test strips using automated urine test strip analysers is a well-established practice in modern-day urinalysis. They can measure calcium , blood, glucose, bilirubin, urobilinogen, ketones, leukocytes, creatinine , microalbumin , pH, ascorbic acid and protein.
By testing for UUN, clinicians can assess one's nitrogen balance. Calculating nitrogen balance is a useful tool in assessing adequacy of protein provision in clinical setting in: Patients with questionable protein intake. Patients with confirmed or suspected protein digestion and absorption problems.
Anion gap can be classified as either high, normal or, in rare cases, low. Laboratory errors need to be ruled out whenever anion gap calculations lead to results that do not fit the clinical picture. Methods used to determine the concentrations of some of the ions used to calculate the anion gap may be susceptible to very specific errors.
In orthostatic albuminuria urine protein excretion returns to normal while in a supine position, such as laying down. Orthostatic albuminuria is the most common cause of isolated proteinuria in those under 20. [5] The prevalence of orthostatic albuminuria is suspected to be between 2 and 5%, [6] however some studies suggest that it is more ...
Tryptophan 7-halogenase is a member of a class of enzymes known as flavin-dependent halogenases. Prior to tryptophan 7-halogenase's discovery, it was thought that all halogen atoms in metabolites were incorporated by the action of haloperoxidases, another class of halogenases dependent on metal centers such as vanadium or heme, or perhydrolases, a class of halogenases that generates peracids ...
Pathway resources and types of pathway analysis using databases like KEGG, Reactome and WikiPathways. [1]Pathway is the term from molecular biology for a curated schematic representation of a well characterized segment of the molecular physiological machinery, such as a metabolic pathway describing an enzymatic process within a cell or tissue or a signaling pathway model representing a ...
There is limited protein sequence coverage by identified peptides, loss of labile PTMs, and ambiguity of the origin for redundant peptide sequences. [7] Recently the combination of bottom-up and top-down proteomics, so called middle-down proteomics, is receiving a lot of attention as this approach not only can be applied to the analysis of large protein fragments but also avoids redundant ...