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ER-positive is one of the Receptor statuses identified in the classification of breast cancer.Receptor status was traditionally considered by reviewing each individual receptor (ER, PR, her2) in turn, but newer approaches look at these together, along with the tumor grade, to categorize breast cancer into several conceptual molecular classes [1] that have different prognoses [2] and may have ...
This is a list of major breast cancer cell lines that are ... List of cell lines. Cell line Primary tumor Origin of cells Estrogen receptors Progesterone receptors ...
Estrogen receptors are over-expressed in around 70% of breast cancer cases, referred to as "ER-positive", and can be demonstrated in such tissues using immunohistochemistry. Two hypotheses have been proposed to explain why this causes tumorigenesis , and the available evidence suggests that both mechanisms contribute:
The commercial test is marketed for use in breast cancer irrespective of estrogen receptor (ER) status. [72] The test is run on formalin fixed, paraffin-embedded tissue. MammaPrint traditionally used rapidly frozen tissue [39] but a room temperature, molecular fixative is available for use within 60 minutes of obtaining fresh tissue samples. [75]
It is used as endocrine therapy for women with estrogen or progesterone receptor-positive, stage 4 or recurrent metastatic breast cancer [7] and has demonstrated similar efficacy compared to tamoxifen as adjuvant treatment of breast cancer and in the treatment of metastatic breast cancer. [6]
Elle Macpherson says she had breast cancer, a diagnosis she kept secret for seven years. The supermodel rejected chemotherapy and choose holistic treatment.
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