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Ibuprofen, an analgesic and non-steroidal anti-inflammatory drug (NSAID), [1] is sold under many brand-names around the world. The most common are Brufen (its earliest registered trademark), Advil, Motrin, and Nurofen .
Ibuprofen is a weaker anti-inflammatory agent than other NSAIDs. [10] Ibuprofen was discovered in 1961 by Stewart Adams and John Nicholson [12] while working at Boots UK Limited and initially marketed as Brufen. [13] It is available under a number of brand names, including Advil, Motrin, and Nurofen.
Non-steroidal anti-inflammatory drugs[1][3] (NSAID) [1] are members of a therapeutic drug class which reduces pain, [4] decreases inflammation, decreases fever, [1] and prevents blood clots. Side effects depend on the specific drug, its dose and duration of use, but largely include an increased risk of gastrointestinal ulcers and bleeds, heart ...
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Ibuprofen/paracetamol. Ibuprofen/paracetamol, sold under the brand name Combogesic among others, is a fixed-dose combination of two medications, ibuprofen, a non-steroidal anti-inflammatory drug (NSAID); and paracetamol (acetaminophen), an analgesic and antipyretic. [6] It is available as a generic medication. [9][10][11]
Right: chemical structure of ibuprofen. The profens are a class of nonsteroidal anti-inflammatory drugs. [1] Profens are also known as 2-arylpropionic acids to reflect their chemical structure. [2] The most common example of a profen is ibuprofen, which has been sold under the brand name Profen among others. Other drugs in the class include:
Hydrocodone/ibuprofen (INNs), sold under the brand name Vicoprofen, is a fixed-dose combination analgesic medication used in short-term therapy to relieve severe pain. [3][4] Vicoprofen combines the analgesic and antitussive properties of hydrocodone with the analgesic, anti-inflammatory, and antipyretic properties of ibuprofen. [1]
The brand first entered the American market in 1984 through Whitehall [3] (itself a division of Wyeth, which was purchased by Pfizer in 2009), [4] the same year Ibuprofen gained Food and Drug Administration approval for over-the-counter sales in the United States (being available via prescription since 1974). [5]