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  2. Epidermolysis bullosa - Wikipedia

    en.wikipedia.org/wiki/Epidermolysis_bullosa

    Junctional epidermolysis bullosa (JEB) is an inherited disease affecting laminin and collagen. This disease is characterized by blister formation within the lamina lucida of the basement membrane zone [ 13 ] : 599 and is inherited in an autosomal recessive manner.

  3. Epidermolysis bullosa dystrophica - Wikipedia

    en.wikipedia.org/wiki/Epidermolysis_bullosa...

    Epidermolysis bullosa dystrophica or dystrophic EB (DEB) is an inherited disease affecting the skin and other organs. [ 1 ] [ 2 ] "Butterfly child" is the colloquial name for children born with the disease, as their skin is seen to be as delicate and fragile as the wings of a butterfly.

  4. 20-Year-Old with 'Butterfly' Skin Disease Is Striving for ...

    www.aol.com/20-old-butterfly-skin-striving...

    In 2017, PEOPLE spoke to Brandon Joseph, who is living with the rare disease epidermolysis bullosa. While many patients die during infancy, Joseph is now thriving at 20. Andrea Pett-Joseph.

  5. Laminopathy - Wikipedia

    en.wikipedia.org/wiki/Laminopathy

    Laminopathies and other nuclear envelopathies have a large variety of clinical symptoms including skeletal and/or cardiac muscular dystrophy, lipodystrophy and diabetes, dysplasia, dermo- or neuropathy, leukodystrophy, and progeria (premature aging). Most of these symptoms develop after birth, typically during childhood or adolescence.

  6. Jonny Kennedy - Wikipedia

    en.wikipedia.org/wiki/Jonny_Kennedy

    Jonathan "Jonny" Kennedy (4 November 1966 – 26 September 2003) was a British man who had a rare inherited condition known as dystrophic epidermolysis bullosa (EB or DEB). Kennedy ultimately died of skin cancer , a complication of EB.

  7. Collagen, type VII, alpha 1 - Wikipedia

    en.wikipedia.org/wiki/Collagen,_type_VII,_alpha_1

    The inherited disease, dystrophic epidermolysis bullosa, is caused by recessive or dominant mutations in COL7A1. [17] Recessive dystrophic epidermolysis bullosa, the most severe type of epidermolysis bullosa, has two subtypes, generalized intermediate and generalized severe, which have been linked to different mutations in the COL7A1 gene.

  8. Epidermolysis bullosa simplex - Wikipedia

    en.wikipedia.org/wiki/Epidermolysis_bullosa_simplex

    Epidermolysis bullosa simplex (EBS) is a disorder resulting from mutations in the genes encoding keratin 5 or keratin 14. [ 1 ] : 598 [ 2 ] It is one of the major forms of epidermolysis bullosa , a group of genetic conditions that cause the skin to be very fragile and to blister easily.

  9. Coma blister - Wikipedia

    en.wikipedia.org/wiki/Coma_blister

    Epidermolysis bullosa (EB) is a genetic disease that causes the skin to be extremely fragile and individuals with the disease are prone to blisters, even with minimal friction and trauma. There are thirty subtypes of epidermolysis bullosa which are arranged into four major categories: EB simplex (EBS), dystrophic EB (DEB), kindler EV, and ...

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