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The isostere concept was formulated by Irving Langmuir in 1919, [3] and later modified by Grimm. Hans Erlenmeyer extended the concept to biological systems in 1932. [ 4 ] [ 5 ] [ 6 ] Classical isosteres are defined as being atoms, ions and molecules that had identical outer shells of electrons, This definition has now been broadened to include ...
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It is also an isostere of xanthine, the normal substrate for the enzyme. [6] Alloxanthine is considered a non-classical bioisostere because of the scaffold change. Silafluofen is an isostere of pyrethroid insecticides.
Pages for logged out editors learn more. Contributions; Talk; Isosteric
In organic chemistry, endo–exo isomerism is a special type of stereoisomerism found in organic compounds with a substituent on a bridged ring system. [1] The prefix endo is reserved for the isomer with the substituent located closest, or "syn", to the longest bridge.
Adamantane is an organic compound with formula C 10 H 16 or, more descriptively, (CH) 4 (CH 2) 6.Adamantane molecules can be described as the fusion of three cyclohexane rings. The molecule is both rigid and virtually stress-free.
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Schematic diagram of topochemical polymerization, the monomer is first crystallized and polymerized to give the polymer product. Topochemical polymerization is a polymerization method performed by monomers aligned in the crystal state.