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Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [11] It is used either alone or with other antibiotics to treat pelvic inflammatory disease , endocarditis , and bacterial vaginosis . [ 11 ]
Praziquantel as a single dose (25 mg/kg) is the current treatment of choice for hymenolepiasis and has an efficacy of 96%. Single-dose albendazole (400 mg) is also very efficacious (>95%). [citation needed] A three-day course of nitazoxanide is 75–93% efficacious. The dose is 1 g daily for adults and children over 12; 400 mg daily for ...
The maximum plasma concentration achieved after oral administration occurred 5–8 hours after dose. [7] Steady state maximum concentration with low-fat meal conditions at the 400 mg once daily dose was found to be 2.1 ± 1.1 μg/mL. It is recommended that venetoclax be administered with a meal. [7]
This antibiotic is not recommended for children and 75 and up of age: Inactivates enolpyruvyl transferase, thereby blocking cell wall synthesis Fusidic acid: Fucidin: Metronidazole: Flagyl: Infections caused by anaerobic bacteria; also amoebiasis, trichomoniasis, giardiasis: Discolored urine, headache, metallic taste, nausea; alcohol is ...
In areas of low clarithromycin resistance, including the United States, a 14-day course of "triple therapy" with an oral proton pump inhibitor, clarithromycin 500 mg, and amoxicillin 1 g (or, if penicillin allergic, metronidazole 500 mg), all given twice daily for 14 days, is recommended for first-line therapy. This regimen can achieve rates of ...
That immediately gets the drug's concentration in the body up to the therapeutically-useful level. First day: 1000 mg; the body clears 100 mg, leaving 900 mg. On the second day, the patient takes 100 mg, bringing the level back to 1000 mg; the body clears 100 mg overnight, still leaving 900 mg, and so forth.
The dosage may be increased up to 6 mg/kg/dose as needed, but not exceed the maximum dose for adults. For children with diseases other than above: 3 mg/kg/dose, 3 times a day after meals. The dosage may be adjusted according to the disease or the patients age and symptoms, but not exceed the maximum dose for adults.
If azithromycin was prescribed as initial therapy, then give doxycycline 100 mg twice daily for 7 days plus metronidazole 400 – 500 mg twice daily for 5 – 7 days; Moxifloxacin 400 mg orally once daily for 7 – 14 days can be given with use of caution, if macrolide-resistant M. genitalium infection is demonstrated [9]