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Amlodipine works partly by vasodilation (relaxing the arteries and increasing their diameter). [10] It is a long-acting calcium channel blocker of the dihydropyridine type. [10] Amlodipine was patented in 1982, and approved for medical use in 1990. [12] It is on the World Health Organization's List of Essential Medicines. [13]
rotated the structure to bring more correspondence with 3D-ball image of amlodipine molecule: 08:13, 21 July 2013: 561 × 326 (8 KB) Vaccinationist: slightly improved look: 03:22, 1 June 2007: 334 × 153 (20 KB) DoSiDo: subscript: 17:15, 19 May 2007: 334 × 153 (19 KB) DoSiDo: corrected RDF: 03:11, 17 May 2007: 334 × 153 (17 KB) DoSiDo ...
English: Amlodipine and one of its major metabolites. The amine group is oxidated and the side ester chains are hydrolyzed. The amine group is oxidated and the side ester chains are hydrolyzed. Español: Amlodipino y uno de sus metabolitos principales.
Amlodipine/olmesartan, sold under the brand name Azor, among others is a fixed-dose combination medication used to treat high blood pressure. [5] It contains amlodipine , as the besilate, a dihydropyridine calcium channel blocker , and olmesartan medoxomil , an angiotensin II receptor blocker .
Amlodipine/benazepril, sold under the brand name Lotrel among others, is a fixed-dose combination medication used to treat high blood pressure. [1] It is a combination of amlodipine, as the besilate, a calcium channel blocker, and benazepril, an angiotensin converting enzyme inhibitor. [1] It may be used if a single agent is not sufficient. [1]
Amlodipine/valsartan, sold under the brand name Exforge among others, is a blood pressure lowering combination drug. It contains amlodipine , as the besilate, a dihydropyridine -type calcium channel blocker , and valsartan , an angiotensin II receptor antagonist . [ 6 ]
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In pooled data, from three comparative studies conducted in 200 patients with mild to moderate hypertension, 2.5 mg of levamlodipine was found to be equivalent in its blood pressure lowering efficacy to 5 mg of amlodipine. The average reduction in systolic BP was 19±3 vs 19±4, 20±2 vs 19±3 and 20±2 vs 19±3 mm of Hg recorded in standing ...