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Beta blockers vary in their lipophilicity (fat solubility) and in turn in their ability to cross the blood–brain barrier and exert effects in the central nervous system. [76] Beta blockers with greater blood–brain barrier permeability can have both neuropsychiatric therapeutic benefits and side effects, as well as adverse cognitive effects ...
The Cleveland Clinic classified beta blockers into two categories, cardioselective and nonselective, according to its website. The latter is for medicines that block the B1 receptors found in the ...
Bisoprolol, sold under the brand name Zebeta among others, is a beta blocker which is selective for the beta-1 receptor [7] and used for cardiovascular diseases, [7] including tachyarrhythmias, high blood pressure, angina, and heart failure.
Sotalol is a beta blocker and non-selectively binds to both β 1-and β 2-adrenergic receptors preventing activation of the receptors by their stimulatory ligand (catecholamines). [ 11 ] [ 12 ] It has no intrinsic sympathomimetic activity .
Beta blockers are a type of medication used to treat heart conditions and cardiovascular diseases, like congestive heart failure, heart attacks, coronary artery disease (aka when a buncha gunk ...
Beta-blockers can block beta-1 adrenergic receptors and/or beta-2 adrenergic receptors. Those that block beta-1-adrenergic receptors prevent the binding of endogenous catecholamines (such as epinephrine and norepinephrine), which ultimately reduces blood pressure through decreasing renin and cardiac output release.
These include beta blockers like propranolol, calcium channel blockers like verapamil and diltiazem, cardiac glycosides like digoxin, alpha-2 agonists like clonidine, and lithium, among others. [5] [27] Beta blockers may slow the heart rate to a dangerous level if prescribed with calcium channel blockers. [28]
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