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2-Ethylhexanol exhibits low toxicity in animal models, with LD50 ranging from 2-3 g/kg (rat). [3] 2-Ethylhexanol has been identified as a cause of indoor air quality related health problems, such as respiratory system irritation, as a volatile organic compound. 2-Ethylhexanol is emitted to air from a PVC flooring installed on concrete that had not been dried properly.
Medical gas therapy is a treatment involving the administration of various gases. It has been used in medicine since the use of oxygen therapy. [1] Most of these gases are drugs, including oxygen. [2] Many other gases, collectively known as factitious airs, were explored for medicinal value in the late eighteenth century. In addition to oxygen ...
This page contains tables of azeotrope data for various binary and ternary mixtures of solvents. The data include the composition of a mixture by weight (in binary azeotropes, when only one fraction is given, it is the fraction of the second component), the boiling point (b.p.) of a component, the boiling point of a mixture, and the specific gravity of the mixture.
During induction of general anesthesia, when a large volume of a gas (e.g. nitrous oxide) is taken up from alveoli into pulmonary capillary blood, the concentration of gases remaining in the alveoli is increased. This results in effects known as the second gas effect [1] and the "concentration effect". These effects occur because of the ...
2-Ethylhexanal is the organic compound with the formula CH 3 CH 2 CH 2 CH 2 CH(C 2 H 5)CHO. A colorless liquid, it is produced on a large scale industrially as a precursor to 2-ethylhexanoic acid and 2-ethylhexanol, both used as precursors to plasticizers. It was studied in the detergent industry since the 1930s. [2]
The effect is named after Bernard Raymond Fink (1914–2000), whose 1955 paper first explained it. [1] [4] When a patient is recovering from N 2 O anaesthesia, large quantities of this gas cross from the blood into the alveoli (down its concentration gradient) and so for a short period of time, the O 2 and CO 2 in the
The Meyer-Overton correlation for anaesthetics. A nonspecific mechanism of general anaesthetic action was first proposed by Emil Harless and Ernst von Bibra in 1847. [9] They suggested that general anaesthetics may act by dissolving in the fatty fraction of brain cells and removing fatty constituents from them, thus changing activity of brain cells and inducing anaesthesia.
Naltrexone blocks the opioid receptors, acting opposite to most opioid pain medications. [22] It can be used to negate the effects of opioid painkillers. At doses around one-tenth of the typical dose, naltrexone has been used for pain relief. Low-dose naltrexone is believed to have an anti-inflammatory effect. This is an off-label use and not ...