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Wilms' tumor or Wilms tumor, [3] also known as nephroblastoma, is a cancer of the kidneys that typically occurs in children (rarely in adults), [4] and occurs most commonly as a renal tumor in child patients. [5] [6] It is named after Max Wilms, the German surgeon (1867–1918) who first described it. [7]
WAGR syndrome (also known as WAGR complex, Wilms tumour-aniridia syndrome, aniridia-Wilms tumour syndrome) is a rare genetic syndrome in which affected children are predisposed to develop Wilms' tumour (a tumour of the kidneys), aniridia (absence of the coloured part of the eye, the iris), genitourinary anomalies, and mental retardation. [1]
This is an accepted version of this page This is the latest accepted revision, reviewed on 21 February 2025. Medical condition Kidney cancer Other names Renal cancer Micrograph showing the most common type of kidney cancer (clear cell renal cell carcinoma). H&E stain. Specialty Oncology nephrology Urology Symptoms Blood in the urine, lump in the abdomen, back pain Usual onset After the age of ...
TUCSON, Ariz., June 11 (Reuters) -- An Arizona woman was recovering at home on Wednesday after having a 47.5-pound (21.5 kg) tumor removed from her abdomen during life-saving surgery, doctors said ...
Inactivation of WT1 causes Wilms tumour, and Denys-Drash syndrome (DDS), leading to nephropathy and genital abnormalities. The WT1 protein has been found to bind a host of cellular factors, e.g. p53, a known tumor suppressor. [7] [12] [13] [14] Despite the name, WT1 mutation is found in only about 5-10% of Wilms Tumor cases. [15]
Dactinomycin, also known as actinomycin D, is a chemotherapy medication used to treat a number of types of cancer. [2] This includes Wilms tumor, rhabdomyosarcoma, Ewing's sarcoma, trophoblastic neoplasm, testicular cancer, and certain types of ovarian cancer. [2] It is given by injection into a vein. [2] Most people develop side effects. [2]
In this study, the commonest sites of tumor occurrence were the lower limb and hip (22% of cases), upper limb and shoulder (12% of cases), and head, face, and neck (9% of cases). [7] Another recent study of 25 patients found the commonest sites of IMT were the abdomen (40% of cases) and lung/thoracic wall (32% of cases). [13]
Desmoid tumors may occur in the head and neck, more commonly among children, and tend to be more aggressive than in other extra-abdominal locations. These tumors constitute up to 23% of extra-abdominal cases. [16] Treatment is typically more aggressive due to the increased dangers of a tumor in the area. [29] [34]