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Colposcopy (Ancient Greek: κόλπος, romanized: kolpos, lit. 'hollow, womb, vagina' + skopos 'look at') is a medical diagnostic procedure to visually examine the cervix as well as the vagina and vulva using a colposcope. [1] The main goal of colposcopy is to prevent cervical cancer by detecting and treating precancerous lesions early.
The RANZCOG training program is a six-year structured post-graduate program which leads to certification as a Fellow of RANZCOG (FRANZCOG). FRANZCOG status is the only post-graduate qualification which leads to recognition as a specialist obstetrician & gynaecologist in Australia and New Zealand.
The loop electrosurgical excision procedure (LEEP) is one of the most commonly used approaches to treat high grade cervical dysplasia (CIN II/III, HGSIL) and early stage cervical cancer discovered on colposcopic examination. In the UK, it is known as large loop excision of the transformation zone (LLETZ). It is considered a type of conization. [1]
Endocervical curettage is a medical procedure used to extract cells of the endocervix to visualize under a microscope. Direct cervical visualization, colposcopy, and even endocervical colposcopy are not enough to fully analyze all areas of the endocervical epithelium and thus endocervical curettage is the method of choice in cases where this is necessary.
The cause of CIN is chronic infection of the cervix with HPV, especially infection with high-risk HPV types 16 or 18. It is thought that the high-risk HPV infections have the ability to inactivate tumor suppressor genes such as the p53 gene and the RB gene, thus allowing the infected cells to grow unchecked and accumulate successive mutations, eventually leading to cancer.
A 2005 study found the sensitivity and specificity of cervicography for cervical intraepithelial neoplasia to be 72.3% and 93.2% respectively; [5] however, a 2007 study criticized the sensitivity figure as "likely... inflated" because the "gold standard" of colposcopy/biopsy may have missed cases of cervical intraepithelial neoplasia.
The probe is placed at some distance from the bleeding lesion, and argon gas is emitted, then ionized by a high-voltage discharge (approx 6kV). [1] High-frequency electric current is then conducted through the jet of gas, resulting in coagulation of the bleeding lesion.
Cervical cancer is the 12th-most common cancer in women in the UK (around 3,100 women were diagnosed with the disease in 2011) and accounts for 1% of cancer deaths (around 920 died in 2012). [154] With a 42% reduction from 1988 to 1997, the NHS-implemented screening programme has been highly successful, screening the highest-risk age group (25 ...