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The term diathesis relates to certain features of Dupuytren's disease, and indicates an aggressive course of disease. [32] The presence of all new Dupuytren's diathesis factors increases the risk of recurrent Dupuytren's disease by 71%, compared with a baseline risk of 23% in people lacking the factors. [32]
Treatment with oral tyrosine kinase inhibitor drugs (e.g. imatinib, sorafenib, pazopanib, sunitinib) shows promising success rates. [43] [29] [44] [40] [45] Radiation therapy after surgery may improve outcomes. [15] [45] Despite the condition's hormonal link, anti-hormonal therapies only appear to work in a small subset of patients. [15]
When Dupuytren's disease is at the nodules and cords stage or fingers are at a minimal deformation stage of less than 10 degrees, then radiation therapy is used to prevent further progress of the disease. Radiation therapy is also used post surgery in some cases to prevent the disease continuing to progress.
Doctor reviewing a radiation treatment plan. In radiotherapy, radiation treatment planning (RTP) is the process in which a team consisting of radiation oncologists, radiation therapist, medical physicists and medical dosimetrists plan the appropriate external beam radiotherapy or internal brachytherapy treatment technique for a patient with cancer.
Half got another approach that includes radiation too. Both techniques are considered standard. Which one patients get can depend on where they get treatment. After three years, 57% of those who ...
[clarification needed] Head and neck desmoid fibromatosis is a serious condition due to local aggression, specific anatomical patterns and the high rate of relapse. For children surgery is particularly difficult, given the potential for growth disorders. [6] Treatment includes prompt radical excision with a wide margin and/or radiation.
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The International Commission on Radiological Protection has proposed a model whereby the incidence of cancers increases linearly with effective dose at a rate of 5.5% per sievert. [8] This model is widely accepted for external radiation, but its application to internal contamination has been disputed.
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