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H5N1 influenza virus is a type of influenza A virus which mostly infects birds. H5N1 flu is a concern because its global spread may constitute a pandemic threat. The yardstick for human mortality from H5N1 is the case-fatality rate (CFR); the ratio of the number of confirmed human deaths resulting from infection of H5N1 to the number of those confirmed cases of infection with the virus.
In surveyed areas of Península Valdés, Argentina, seal mortality rates reached 96%. [7] In February 2024 it was estimated that the outbreak of H5N1 in South America had killed at least 600,000 wild birds and 50,000 mammals since 2022. [7]
Data source: Threats to Birds / Top Threats to Birds (U.S. only. Ordered by Median Estimate of Bird Mortality Annually. As of 2017.). U.S. Fish and Wildlife Service (2017). Archived from the original on 13 February 2025. Source states: True estimates of mortality are difficult to determine. However, recent studies have synthesized the best ...
The bird at the center of the worst single-species mortality event in modern history isn’t recovering, scientists say Julianna Bragg, CNN December 26, 2024 at 11:18 AM
While the mortality rate was 0.6 per cent for Covid-19, Redfield said the mortality for the bird flu would probably be “somewhere between 25 and 50 per cent.”
The global spread of H5N1 influenza in birds is considered a significant pandemic threat. While other H5N1 influenza strains are known, they are significantly different on a genetic level from a highly pathogenic, emergent strain of H5N1, which was able to achieve hitherto unprecedented global spread in 2008. [1]
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Influenza A virus subtype H5N1 (A/H5N1) is a subtype of the influenza A virus, which causes the disease avian influenza (often referred to as "bird flu"). It is enzootic (maintained in the population) in many bird populations, and also panzootic (affecting animals of many species over a wide area). [1]