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Neonatal meningitis is a serious medical condition in infants that is rapidly fatal if untreated.Meningitis, an inflammation of the meninges, the protective membranes of the central nervous system, is more common in the neonatal period (infants less than 44 days old) than any other time in life, and is an important cause of morbidity and mortality globally.
Bacteria found in the maternal gastrointestinal or gastrourinary tracts can commonly lead to neonatal infection. Bacterial infections may present as fetal distress at birth (including signs of tachycardia, temperature instability or difficulty breathing), neonatal sepsis, or neonatal meningitis.
E. meningoseptica predominantly causes outbreaks of meningitis in premature newborns and infants in neonatal intensive care units of underdeveloped countries. [citation needed] Some of the outbreaks have been linked to sources such as contaminated lipid stock bottles, contaminated venous catheter lines and nutritional solution, and tap water.
Infections of the central nervous system (CNS) consist of infections primarily of the brain and spinal cord. They include mostly viral infections, less commonly bacterial infections, fungal infections, prion diseases and protozoan infections. Neonatal meningitis is a particular classification by age.
Infection with GBS can cause serious illness and sometimes death, especially in newborns, the elderly, and people with compromised immune systems. The most severe form of group B streptococcal disease is neonatal meningitis in infants, which is frequently lethal and can cause permanent neuro-cognitive impairment.
Neonatal meningitis is the most common presentation of Elizabethkingia for children. Recent studies suggest that approximately 31% of children that have Elizabethkingia pass away from the infection, with an average life expectancy of 27 days from onset of symptoms. [12]
In the western world, GBS (in the absence of effective prevention measures) is the major cause of several bacterial infections of the newborn neonatal infection sepsis, pneumonia, and meningitis, which can lead to death or long-term sequelae. [3] GBS neonatal infection typically originates in the lower reproductive tract of infected mothers.
It can be a cause of neonatal infections. [4] Streptococcus pneumoniae is the main cause of community acquired pneumonia and meningitis in children and the elderly, [5] and of sepsis in those infected with HIV. The organism also causes many types of pneumococcal infections other than pneumonia.
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