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It can cause a black tongue and black stools in some users of the drug when it combines with trace amounts of sulfur in saliva and the colon to form bismuth sulfide. [7] Bismuth sulfide is a highly insoluble black salt, and the discoloration seen is temporary and harmless. Long-term use (more than six weeks) may lead to accumulation and ...
The sixty-year-old patient’s face skin also turned grey, doctors say Cancer patient’s tongue turned black and hairy ‘after rare antibiotics reaction’ Skip to main content
Bismuth subsalicylate (BSS) has both antibacterial and anti-secretory actions that help with diarrhea. [1] Once in the gut, BSS gets broken down into bismuth and salicylic acid. [ 1 ] Bismuth produces other bismuth salts, which blocks the binding and proliferation of bacteria in stomach mucosal cells, leading to a decrease in inflammation in ...
Kussmaul suggests using bismuth compounds, an antibacterial agent, to treat peptic ulcers (bismuth subsalicylate has since been used in many commercial drugs, including Pepto Bismol as part of antibacterial H. pylori treatment). The antibacterial properties of bismuth were not known until much later. [1] 1875
Oral tongue cancer is a cancer that happens in the front two-thirds of the tongue, while oropharyngeal tongue cancer forms at the base of the tongue in the back portion of the mouth and can extend ...
Black hairy tongue syndrome (BHT [4]) is a condition of the tongue in which the small bumps on the tongue elongate with black or brown discoloration, giving a black and hairy appearance. The appearance may be alarming, but it is a harmless condition.
While usually due to aspirin, other possible causes include oil of wintergreen and bismuth subsalicylate. [2] Excess doses can be either on purpose or accidental. [1] Small amounts of oil of wintergreen can be toxic. [2] Diagnosis is generally based on repeated blood tests measuring aspirin levels and blood gases. [1]
Bismuth subsalicylate four times daily reduces rates of travelers' diarrhea. [ 2 ] [ 27 ] Though many travelers find a four-times-per-day regimen inconvenient, lower doses are not effective. [ 2 ] [ 27 ] Potential side effects include black tongue, black stools, nausea, constipation, and ringing in the ears .
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