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Kaposi's sarcoma (KS) is a type of cancer that can form masses on the skin, in lymph nodes, in the mouth, or in other organs. [ 4 ] [ 6 ] The skin lesions are usually painless, purple and may be flat or raised.
Kaposi sarcoma, a rare cancer of the cells that line blood vessels in the skin and mucous membranes, is caused by human herpesvirus 8. Kaposi sarcoma often occurs in patients with acquired immune deficiency syndrome. Kaposi sarcoma, however, has different characteristics from typical soft-tissue sarcomas and is treated differently. [8]
Kaposi's sarcoma-associated herpesvirus (KSHV) is the ninth known human herpesvirus.It is also called Human herpesvirus 8, or HHV-8 in short. [2] This virus causes Kaposi's sarcoma, a cancer commonly occurring in AIDS patients, [3] as well as primary effusion lymphoma, [4] HHV-8-associated multicentric Castleman's disease and KSHV inflammatory cytokine syndrome. [5]
Skin sarcomas are tumors on the surface of or inside the dermal layers (skin). They are small in size compared to other sarcomas which can arise inside muscles, abdominal cavity, retroperineal sites, etc. [1] [2] [3] These sarcomas are rare, but potentially fatal. [4] Some types of sarcoma that can manifest on the skin include: Angiosarcoma
Angiosarcoma is a rare and aggressive cancer that starts in the endothelial cells that line the walls of blood vessels or lymphatic vessels.Since they are made from vascular lining, they can appear anywhere and at any age, but older people are more commonly affected, and the skin is the most affected area, with approximately 60% of cases being cutaneous (skin).
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An osteosarcoma (OS) or osteogenic sarcoma (OGS) is a cancerous tumor in a bone. Specifically, it is an aggressive malignant neoplasm that arises from primitive transformed cells of mesenchymal origin (and thus a sarcoma ) and that exhibits osteoblastic differentiation and produces malignant osteoid .
Dermatofibrosarcoma protuberans (DFSP) [2] is a rare locally aggressive malignant cutaneous soft-tissue sarcoma. DFSP develops in the connective tissue cells in the middle layer of the skin (dermis). [3] Estimates of the overall occurrence of DFSP in the United States are 0.8 to 4.5 cases per million persons per year.