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Evidence suggests both agencies knew about 2,500 deaths of dogs linked to Seresto's flea and tick collars, but took no action and never warned the public. Documents obtained by the Center For ...
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This occurs due to profound hypotension caused by reversal of the alpha 1 effects while the reflex bradycardia is still in effect.). There is a low rate of side effects, largely due to atipamezole's high specificity for the α 2-adrenergic receptor. Atipamezole has a very quick onset, usually waking an animal up within 5 to 10 minutes.
A dog collar is a piece of material put around the neck of a dog. A collar may be used for restraint, identification, fashion, protection, or training (although some aversive training collars are illegal in many countries [1] [2]). Identification tags and medical information are often placed on dog collars. [3]
Further, the FDA does not receive all adverse event reports that occur with a product. Many factors can influence whether or not an event will be reported, such as the time a product has been marketed and publicity about an event. Therefore, FAERS cannot be used to calculate the incidence of an adverse event in the U.S. population.
Serious adverse reactions are serious adverse events judged to be related to drug therapy. A SUSAR (suspected unexpected serious adverse reaction) should be reported to a drug regulatory authority under an investigational license by using the CIOMS form (or in some countries an equivalent form).