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3D cell culture. A 3D cell culture is an artificially created environment in which biological cells are permitted to grow or interact with their surroundings in all three dimensions. Unlike 2D environments (e.g. a Petri dish), a 3D cell culture allows cells in vitro to grow in all directions, similar to how they would in vivo. [1]
Organ-on-a-chip. An organ-on-a-chip (OOC) is a multi-channel 3-D microfluidic cell culture, integrated circuit (chip) that simulates the activities, mechanics and physiological response of an entire organ or an organ system. [1][2] It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS.
Cell culture is a fundamental component of tissue culture and tissue engineering, as it establishes the basics of growing and maintaining cells in vitro. The major application of human cell culture is in stem cell industry, where mesenchymal stem cells can be cultured and cryopreserved for future use. Tissue engineering potentially offers ...
A flask containing human cerebral organoids. A neural, or brain organoid, describes an artificially grown, in vitro, tissue resembling parts of the human brain. Neural organoids are created by culturing pluripotent stem cells into a three-dimensional culture that can be maintained for years. [1][2] The brain is an extremely complex system of ...
Growing human tissue is old hat, but being able to measure activity inside flesh is harder -- any electrical probing tends to damage the cells. But a new breakthrough from Harvard researchers has ...
The nano-scaffold is a three-dimensional structure composed of polymer fibers very small that are scaled from a Nanometer (10 −9 m) scale. [1] Developed by the American military, the medical technology uses a microscopic apparatus made of fine polymer fibers called a scaffold. [2] Damaged cells grip to the scaffold and begin to rebuild ...
Intestinal organoid grown from Lgr5+ stem cells. An organoid is a miniaturised and simplified version of an organ produced in vitro in three dimensions that mimics the key functional, structural, and biological complexity of that organ. [ 1 ] It is derived from one or a few cells from a tissue, embryonic stem cells, or induced pluripotent stem ...
Different models of 3D printing tissue and organs. Three dimensional (3D) bioprinting is the use of 3D printing–like techniques to combine cells, growth factors, bio-inks, and biomaterials to fabricate functional structures that were traditionally used for tissue engineering applications but in recent times have seen increased interest in other applications such as biosensing, and ...