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White patches which have been present for a long period of time have a higher risk. [3] Persons with a positive family history of cancer in the mouth. [3] Candida infection in the presence of dysplasia has a small increased risk. [3] A change in the appearance of the white patch, apart from a change in the color, has a higher risk. [3]
Smokeless tobacco keratosis (STK) [4] is a condition which develops on the oral mucosa (the lining of the mouth) in response to smokeless tobacco use. Generally it appears as a white patch, located at the point where the tobacco is held in the mouth. The condition usually disappears once the tobacco habit is stopped.
It is characterised by presence of small blisters all over the limbs and the mouth. [18] Measles: A highly infectious condition which is caused by measles virus. It most commonly presents in young children who have not been vaccinated. It is characterised by presence of white spots (Koplik's spots) which rupture to form ulcers on the palate. [18]
Stomatitis nicotina is a diffuse white patch on the hard palate, usually caused by tobacco smoking, usually pipe or cigar smoking. [2] It is painless, [4] and it is caused by a response of the palatal oral mucosa to chronic heat.
Leukoedema lesions disappear when the mucosa is stretched, which helps to differentiate it from other white lesions in the mouth. [2] The differential diagnosis is with leukoplakia , oral candidiasis , oral lichen planus , white sponge nevus , morsicatio buccarum , [ 3 ] hereditary benign intraepithelial dyskeratosis and dyskeratosis congenita.
Oral cancer, also known as oral cavity cancer, tongue cancer or mouth cancer, is a cancer of the lining of the lips, mouth, or upper throat. [6] In the mouth, it most commonly starts as a painless red or white patch, that thickens, gets ulcerated and continues to grow.
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Hairy leukoplakia is a white patch on the side of the tongue with a corrugated or hairy appearance. It is caused by Epstein-Barr virus (EBV) and occurs usually in persons who are immunocompromised, especially those with human immunodeficiency virus infection/acquired immunodeficiency syndrome (HIV/AIDS).